Education
2019-2023, Ocean University of China, Marine Biology, Ph.D
2016-2019, Shanghai Ocean University, Marine Science, Master
2012-2016, Dalian Ocean University, Marine Science, Bachelor
Research experiences
2025- Present, Ocean University of China, Associate Professor
2023-2025, Ocean University of China, Postdoctoral Associate
Main research directions and interests
My research interests center on the evolution of ancient chromosomes, sex chromosomes, and chromosomal rearrangements, as well as the unique traits of various animal species. I employ a multi-omics approach to investigate these evolutionary dynamics and the specific characteristics of different species.
Representative publications (#equal contribution; *corresponding author)
1.Lian, S.#, Wang, W.#,*, Liu, Y.#, Lu, M.#, Han, W.#, Luo, J.#, Zhang, X.#, Pang, Y.#, Li, Y.#, Li, Y., Dang, X., Wang, P., Qin, Y., Tan, N., Zhang, F., Zhang, J., Gao, S., Zhang, R., Guo, L., Jiang, L., Zhang, P., Zhang, Y., Qu, Z., Pan, S., Zhang, Y., Hu, N., Chen, Y., Cao, Y., Li, W., Chen, X., Shi, J., Yang, S., Li, Y., Song, Q., Bao, L., Li, Y., Liu, X., Wang, J., Zhang, L., Li, R., Yu, X., Yang, T., Chen, J., Li, L., Zhang, M., Li, L., Zhang, R., Li, H., Gu, Y., Xu, X., Yang, H., Bao, Z., Burns, CG., Burns, CE., Kelly, RG., Wang, J., Zhao, Y., Su, Y., Fan, G., Liu, Q.*, Wang, S.*, Fei, J.*, Pan, S.*, Zhao, L.*. (2026) Spatially resolved single-cell atlas reveals the macroevolutionary trajectory of animal hearts. Science. (Online advanced publication, https://www.science.org/doi/10.1126/science.adw0855)
2.Han, W. #, Liu, L. #, Wang, J. #, Wei H. #, Li, Y. #, Zhang, Lj. #, Guo, Z., Li, Y., Liu, T, Zeng, Q., Xing, Q., Shu, Y., Wang, T., Yang, Y., Zhang, M., Li, R., Yu, J., Pu, Z., Lv, J., Lian, S., Hu, J., Hu, X., Bao, Z., Bao, L.*, Zhang, Ll.*, Wang, S.*. (2022). Ancient homomorphy of molluscan sex chromosomes sustained by reversible sex-biased genes and sex determiner translocation. Nature Ecology & Evolution 6, 1891-1906. (Cover story, Behind the Paper: The 'forever-young' secret of scallop sex chromosomes: exceptions to the 'general' rules)
3.Ye, N. #,*, Han, W. #, Toseland, A, Wang, Y., Fan, X., Xu, D., Oosterhout,C, Sea of Change Consortium, Grigoriev, I., Tagliabue, A, Zhang, J., Zhang, Y., Ma, J, Qiu, H., Li Y., Zhang X *, Mock, T.*. (2022). The role of zinc in the adaptive evolution of polar phytoplankton. Nature Ecology & Evolution 6, 965-978. (NEE News & Views: Polar algae flaunt their zinc assets)
4.Han W., Wu S., Ding H., Wang M., Wang M., Bao Z., Wang B.*, Hu J.*.(2023). Improved chromosomal-level genome assembly and re-annotation of leopard coral grouper. Scientific Data 10, 156.
5.Li, S.#, Wang, D.#, Liu, T., Liu, S., Ni, K., Zhang, L., Wang, S., Han, W.*, Bao, L.*. (2026) Development of structural variation-based sex-specific markers and a non-destructive visual assay for sex identification in the sea cucumber (Apostichopus japonicus). Aquaculture 625: 744339.
6.Wu, S.#, Zeng, Q.#, Han, W.#, Wang, M., Ding, H., Teng, M., Wang, M, Li, P, Gao, X., Bao, Z., Wang, B.*, Hu, J.*. (2023). Deciphering the population structure and genetic basis of growth traits from whole-genome resequencing of the leopard coral grouper (Plectropomus leopardus). Zoological Research. 45(2) 1-12.
7.Chen, C., Lium J., Zhuangm R., Nim K., Wangm M., Lim Y., Wangm J., Wang, S., Han, W.*, Bao, L.*. (2026) Genome-wide 6mA map unveils epigenetic adaptation in deep-sea limpet. Ecology and Evolution. 16: e73449.
8.Zhang, X.#, Han, W.#, Fan, X., Wang, Y., Xu, D., Sun, K., Zhang, Y., Ma, J., Ye, N.*. (2023) Gene duplication and functional divergence of new genes contributed to the polar acclimation of Antarctic green algae. Marine Life Science Technology 5(4), 511–524.
9.Yu, X.#, Zhao, B.#, Han, W.#, Liu, Y.#, Wang Z, Zhu X, Wang Y, Fang L, Wang S, Hu J, Bao Z. (2026) The first near-complete telomere-to-telomere genome of Atlantic salmon (Salmo salar) provides insights for genetic diversity. The Innovation Life. 4: 100236.
10.Teng, L. #, Han, W.#, Fan, X., Zhang, X., Xu, D., Wang, Y., Rahman, S., Pellegrini, M., L. Mock, T., Ye, N.*. (2021). Integrative analysis of chloroplast DNA methylation in a marine alga—Saccharina japonica. Plant Molecular Biology 105, 611–623. (Cover story)
11.Han, W., Fan, X., Teng, L., Kaczurowski, M.J.S., Zhang, X., Xu, D., Yin, Y., and Ye, N.*. (2019). Identification, classification, and evolution of putative xylosyltransferases from algae. Protoplasma 256, 1119-1132.
12.Chen, X.#, Han, W.#, Chang, X., Tang, C., Chen, K., Bao, L., Zhang, L., Hu, J., Wang, S.*, Bao, Z.* (2025) . High-quality genome assembly of the azooxanthellate coral Tubastraea coccinea (Lesson, 1829) . Scientific Data 12, 507.
13.Chang, X .#, Han, W.#, Chen, X., Tang, C., Wang, D., Huang, H., Li, Y., Chen, K., Hu, J., Bao, Z., Chen, H.*, Wang, S.*(2025) . Re-annotation improved large-scale assembly of the reef-building coral Acropora intermedia. Scientific Data 12, 1504.
14.Tang, C., Han, W.*, Ke, S., Wang, D., Chen, K., Bao, L., Guan, L., Hu, J., Wang, S., Bao, Z. (2025). Complete mitochondrial genome and phylogenetic analysis of Podabacia crustacea (Pallas, 1766). Mitochondrial DNA Part B, 10(7), 537–542.
